Bone Abstracts

Numerous studies in adult patients with type 1 diabetes (T1D) described an association with reduced bone mineral density, altered bone geometry and osteoporosis. Epidemiologic data on hip fractures demonstrate an increased risk in a large adult population with T1D. Diabetes is therefore categorized as adversely affecting the skeleton.In children and adolescence observations have been more controversial regarding bone mineral content, bone mineral density...

Biographical DetailsS Bechtold-Dalla Pozza is a Consultant Pediatric Endocrinologist working at the Department of Endocrinology and Diabetology of the Dr von Haunersches Kinderspital, Ludwig-Maximilians University, Munich, Germany. She completed her pediatric training at the department of Pediatrics at the University Children’s Hospital, Munich, following a clinical and research fell...

The aim of the study is to determine whether there is an imbalance between bone formation and bone resorption in nonbacterial osteitis. The osteoclast inhibitor pamidronate has been successfully used in nonbacterial osteitis. It is assumed, that there is any mismatch in the pathophysiology of osteoblasts or osteoclasts. Until now, we have no known publications on bone metabolism in nonbacterial osteitis. We chose osteoprotegerin (OP) and alkaline phosphatase (AP) as markers of...

Background/aims: Glucocorticoid treatment may influence bone and muscle development in patients with congenital adrenal hyperplasia (CAH). This study evaluates bone mineral density (BMD), bone geometry and muscle mass longitudinally throughout childhood.Methods: Eighteen patients (ten males, eight females) with classical CAH were included. BMD, bone geometry and muscle mass were measured using peripheral quantitative computed tomography (pQCT) in prepube...

Objective: Muscular dystrophy is characterized by lower skeletal muscle quality, lower muscle strength and physical performance. The aim of the study was to assess regional muscle density and its correlation with regional muscle area in Duchenne muscular dystrophy (DMD) subjects and able bodied controls.Method: Skeletal muscle pQCT (peripheral quantitative computed tomography) scans at the non-dominant forearm were performed in patients with muscle dystr...